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Department of Neurology

Scientific work

 

Responsible employees:

Sokolova Larysa Ivanivna

 

 

 

 

 

 

 

 

 

Dovbonos Tetiana Anatoliivna

Довбонос

 

 

 

 

 

 

 

 

 

Kyiv City Clinical Hospital No. 4

Research Areas

  • State Registration Number: 0122U000487
  • Research Topic: Investigate the pathomorphosis of vascular and autoimmune diseases of the nervous system against the background of COVID-19.
  • Research Supervisor: Head of the Department, Doctor of Medical Sciences, Professor Mariia Prokopiv

Scientific Developments, Achievements, Priorities

  • Developed and adapted scales for assessing neurological deficits in stroke for broad use in neurological practice.
  • Made significant contributions to the study and dissemination of knowledge about TIA and stroke subtypes, including their prognosis and outcomes in national angioneurology.
  • Developed a scale to assess stroke risk after TIA, depending on its pathogenesis.
  • Defined the distribution of ischemic stroke subtypes and the clinical and paraclinical characteristics of the disease in young patients.
  • Investigated the pathogenetic role of stress hyperglycemia in ischemic stroke and its impact on stroke outcomes. Summarized and supplemented the pathophysiological mechanisms of dysphagia development in stroke and developed a method for its diagnosis and severity assessment.
  • Established the relationship between the localization of ischemic lesions in the cerebellum and/or brainstem, as well as the volume of infarction, with the development of systemic dizziness and neurocognitive disorders in patients with acute ischemic stroke in the vertebrobasilar basin.
  • Conducted clinical and experimental research on the role of viral infection in the development, course, and outcomes of acute ischemic stroke.
  • Pathogenetically justified the need to reduce manifestations of local post-ischemic inflammation and proposed methods for its correction.
  • Demonstrated the significance of coagulopathy as an essential component of the pathogenesis of ischemic stroke in SARS-CoV-2 positive patients.
  • Substantiated the advisability of an optimized system of prevention and medical care for patients with cerebrovascular diseases in the context of a modern metropolis.
  • Demonstrated the potential effectiveness of stroke treatment in an integrated stroke unit by analyzing the therapeutic impact on the dynamics and degree of neurological function recovery at different stages of the disease.
  • Studied the clinical-neurophysiological, neuroimaging, and hemodynamic profiles of migraine status and migraine-induced stroke.
  • Examined the spectrum of motor (spasticity), psycho-emotional, cognitive, and sexual disorders in patients with multiple sclerosis and proposed methods for their correction.
  • Analyzed the clinical, neurophysiological, and therapeutic aspects of peripheral nervous system involvement in patients with multiple sclerosis and chronic inflammatory demyelinating polyneuropathy.
  • Developed an algorithm for the diagnosis of acute disseminated encephalomyelitis and clinically isolated syndrome, and proposed mathematical models for predicting their progression to multiple sclerosis.
  • Evaluated the potential impact of COVID-19 on the course of autoimmune neurological diseases (myasthenia gravis, multiple sclerosis, Guillain-Barré syndrome).
  • Proposed effective treatment regimens for multiple sclerosis depending on the course, disability degree, stage, and duration of the disease, improving patients’ quality of life.
  • Studied the risk factors for the occurrence of acute ischemic stroke and the clinical profile of patients with ischemic stroke against the background of COVID-19.

Defended Dissertations Over the Last 10 Years

Doctoral Dissertations:

  • Volodymyr Melnyk: “Course of Ischemic Stroke Depending on Genetic Polymorphism and Changes in the Hemostasis System.” 2015.
  • Tetiana Kobys: “Course and Prognosis of Demyelinating Process Activity in Patients with Multiple Sclerosis and Methods for Its Correction.” 2016.
  • Mariia Prokopiv: “Medical and Social Justification of an Optimized System for Prevention and Medical Care for the Population with Cerebrovascular Diseases at the Megapolis Level in the Context of Healthcare Reform.” 2021.
  • Nataliia Turchyna: “Clinical and Experimental Justification of the Role of Viral Infection in the Development, Course, and Outcomes of Acute Ischemic Stroke.” 2021.
  • Yurii Flomin: “Dynamics and Degree of Neurological, Cognitive, and Functional Recovery in Patients with Cerebral Stroke Treated in an Integrated Stroke Unit at Different Stages of the Disease.” 2023.

PhD Dissertations:

  • Maryna Sepikhanova: “Course, Diagnosis, and Treatment of Multiple Sclerosis in Patients of Different Age Groups.” 2015.
  • Svitlana Rogoza: “Clinical and Neuroimaging Characteristics and Prognosis of the Course of Supratentorial Intracerebral Hemorrhages in Patients with Arterial Hypertension.” 2016.
  • Hanna Trepet: “Isolated Cerebellar Infarcts: Features of Coordination and Neuropsychological Disorders in the Dynamics of Treatment in the Acute and Recovery Periods.” 2017.
  • Nataliia Bobryk-Zahoruiko: “Clinical and Epidemiological Characteristics of Multiple Sclerosis in the Volyn Region.” 2017.
  • Vasyl Babenko: “Ischemic Stroke Against the Background of Metabolic Syndrome: Features of Clinical Course and Pathogenetic Therapy.” 2017.
  • Viktoriia Shandyuk: “Features of the Acute and Recovery Periods of Atherothrombotic and Cardioembolic Subtypes of Ischemic Stroke Depending on the State of the Fibrinolytic System.” 2018.
  • Yuliia Khizhniak: “Clinical-Neuropsychological Correlations in Patients with Multiple Sclerosis.” 2019.
  • Yuliia Didkova: “Clinical-Neurophysiological, Neuroimaging, and Hemodynamic Characteristics of Migraine Complications (Migraine Status and Migraine-Induced Stroke).” 2019.
  • Nataliia Radzikhovska: “Sexual Dysfunction in Patients with Multiple Sclerosis: Dependence on Disease Course and Treatment.” 2017.
  • Yaroslav Nebor: “Clinical Course and Prognosis of Ischemic Stroke in Young Patients.” 2021.
  • Nataliia Domres: “Clinical and Paraclinical Characteristics and Treatment of Spasticity in Patients with Multiple Sclerosis.” 2021.

Over the Last 10 Years, the Department Staff Has Published:

  • Textbooks: 2
  • Manuals: 4
  • Monographs: 1

Published Articles

  • Scopus: 34
  • Web of Science: 13
  • Specialized Journals (Category B, MES of Ukraine): 75

Published Abstracts

  • Theses: 81

Presentations at Scientific Forums

  • Total Presentations: 256

Cumulative H-index

  • Scopus: 14
  • Google Scholar: 56
  • Web of Science: 6

Patents Obtained

  • Total Patents: 9

New Diagnostic, Treatment, and Prevention Methods Developed and Implemented

  • Total Methods: 9

The results of the conducted research have been integrated into the diagnostic and treatment processes at the neurological departments of St. Michael’s Clinical Hospital, Kyiv City Hospitals No. 3, 4, 6, and 9.

Puplications 

 

An annual scientific and practical conference with international participation is held at the department

 

Continuous Professional Development (CPD) for Physicians

The Department of Neurology at Bogomolets National Medical University offers thematic improvement courses for physicians on a contractual basis.
In 2025, a specialization course in neurology is planned for physician attendees on a contractual basis.

Target audience for the Neurology Specialization Course:

  • General practitioners and family doctors (course duration: 5 months).
  • Emergency medicine physicians (course duration: 3 months).
  • Neurologists who have not practiced for over three years (course duration: 3 months).

The Institute of Postgraduate Education at Bogomolets National Medical University invites applications for the thematic improvement course “Epilepsy and Non-Epileptic Paroxysmal Conditions,” with a duration of 2 weeks (78 hours), to be held at the university’s Department of Neurology.
Course Dates: October 21, 2024 – November 1, 2024.
Target audience for the course: General practitioners, family doctors, neurologists, pediatric neurologists, and therapists.
The classes will be conducted in a blended (in-person and online) format.

Topics to be covered in the course include:
Diagnostic and treatment approaches for epilepsy in adults and children using functional diagnostic methods, discussion of epilepsy and seizure classification, clinical diagnostic features of epileptic seizures and their main differences from non-epileptic seizures using clinical case studies. Based on the current classification of epilepsy and epileptic syndromes, diagnostic criteria for the most common forms of childhood epilepsy will be presented, as well as modern approaches to antiepileptic therapy and specific medication management for epilepsy patients.

The course is fee-based. Upon completion, the physician will receive a certificate awarding 50 points towards their professional portfolio, according to the criteria for continuous professional development and qualification enhancement for physicians.

Required documents for enrollment:

  • Passport.
  • University degree diploma.
  • Name change document (if the physician’s surname differs between the passport and diploma).

For additional information, please contact the Institute of Postgraduate Education at Bogomolets National Medical University or the course coordinator:

Contact number: +380675093804 – Associate Professor of the Department of Neurology – Viktoria Svystilnyk.