Department of Internal Medicine №4
SCIENTIFIC WORK
Responsible for scientific work:
Motsak T – Ph.D., Associate Professor of Internal Medicine №4,
phone +380936365516
Email address – motsaktm@ukr.net
The priority areas of scientific work of the Department of Internal Medicine №4 are the following sections of modern cardiology, rheumatology and internal medicine:
- Diagnosis and treatment of patients with comorbid pathology of internal organs
- Imbalance of the amino acid composition of blood plasma as a possible pathogenetic link in the development of atherosclerosis and coronary heart disease
- Treatment of heart rhythm disorders in post-infarction patients with type 2 diabetes
- Features of treatment of patients with generalized atherosclerosis
- The state of the composition of the intestinal microbiota in patients with coronary heart disease with paroxysmal form of atrial fibrillation
- The role of disruption of tryptophan and serotonin metabolism in patients with generalized atherosclerosis
- ASA-induced gastropathy in patients with high cardiovascular risk.
- The role of humoral and cellular immunity disorders in the development of atherosclerosis and acute coronary syndrome
- Forecasting the course of unstable angina by studying the fatty acid spectrum of platelets
- Features of diagnosis and treatment of ischemic heart disease in patients with concomitant pancreatitis
- Postprandial hypotension, mechanisms of development, diagnosis, treatment
- Obesity is a risk factor for the development of hyperinsulinemia in patients with essential arterial hypertension
- The role of violations of the fatty acid spectrum of lymphocytes in the development of coronary heart disease
- Obstructive sleep apnea syndrome: relationship to cardiovascular disease
- The state of activity of the dopaminergic system as one of the factors in the development of arterial hypertension and obesity
- Treatment of systolic heart dysfunction in patients with type 2 diabetes who have undergone a non-Q myocardial infarction
- Determination of changes in blood lipid spectrum indicators in post-infarction patients with type 2 diabetes
- Medicinal correction of disorders of the fatty acid spectrum of erythrocyte membranes in patients with a permanent form of atrial fibrillation
- Hyperinsulinemia on long-term prognosis in patients with arterial hypertension and metabolic disorders
In recent years, scientists of the department have conducted and continue to conduct research on the following topics:
- Use of pemafibrate to reduce cardiovascular complications by lowering triglycerides in patients with diabetes mellitus)
- Open-label phase 3b study to evaluate the long-term safety and efficacy of vedolizumab for subcutaneous administration in patients with ulcerative colitis and Crohn’s disease
- Impaired hemodynamics, coronary circulation and ectopic myocardial activity in patients with coronary heart disease with concomitant diabetes mellitus, methods of drug correction
- Long-term study of the effects to assess the reduction of residual risk with statin in combination with Epanov in patients with high cardiovascular risk hypertriglyceridemia (“STRENGTH”)
- Changes in the amino acid spectrum of blood plasma in patients with coronary heart disease with cardiac arrhythmias and their drug correction
- Influence of serum amino acid spectrum in type 2 diabetes mellitus on cardiovascular risk indicators in patients with coronary heart disease and methods of drug correction
- Features of the course of unstable angina depending on the functioning of the hemostasis system in different variants of statin therapy
- Clinicopathogenetic justification for the use of cilostosol in patients with complicated hypertension
- Comprehensive assessment of hemodynamic and metabolic disorders in patients with coronary heart disease combined with type II diabetes mellitus and possible drug correction.
- Violation of the fatty acid spectrum of platelets, immunological status and amino acid spectrum of blood serum and the possibility of drug correction)
- Changes in the fatty acid spectrum of erythrocyte membranes with a constant form of atrial fibrillation
- Disorders of lipid, carbohydrate and protein metabolism in patients with coronary heart disease with concomitant hypertension, the possibility of drug correction
Topic of the scientific work of the Department of Internal Medicine No. 4 ” Features of lipid metabolism, proteins, neurotransmitters and hemodynamics in patients with generalized atherosclerosis and secondary prevention of cardiovascular events.” All Scientific and Pedagogical Workers of the Department take an active part in the scientific work. For the year 2023, the scientific work of the Department of Internal Medicine No. 4, employees took part in writing a monograph and are members of the editorial board of scientific journals.
In 2023, the NPP of the department published: 28 articles (11 of them international), 52 theses (28 of them international); 8 publications in scientometric databases Scopus and Web of Science. The results of the scientific work were highlighted in reports at Ukrainian and international conferences – 24 (of which 15 were international). Professors of the department are members of specialized councils for dissertation defense; 2 doctoral dissertations and 5 dissertations for the Ph.D. degree are completed at the department.
Employees of the department are members of international specialized organizations
Head of the department, professor Lyzogub V.G. – Member of the Presidium of the Republican Society of Therapists of Ukraine, Deputy Chairman of the Academic Council for Cardiology and Rheumatology at NMU, active member of the European Society of Cardiology (ESC).
Associate professor Motsak T.M. – member of the European Atherosclerosis Association (EAS), Member of Council on Basic Cardiovascular Science, European Society of Cardiology (ESC)
Associate professor Melnychuk I.O. – member of the European Association of Cardiologists.
Assistant Tyravska Yu.O. – member of the European Association of Cardiology, the European Association of Hematologists, the International Association of Thrombosis and Hemostasis
