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Department of Internal Medicine №2

Scientific work

 

Responsible for scientific work: Professor of the Department of Internal Medicine No. 2, Rudenko Yu.V.

 

 

The priority areas of scientific work of the Department of Internal Medicine No. 2 are the following sections of modern cardiology, rheumatology and internal medicine:

  • Features of diagnosis and treatment of coronary heart disease in patients with chronic obstructive pulmonary diseases
  • Pathophysiological mechanisms of development, diagnosis, treatment of acute coronary syndromes
  • Early Left Ventricular Systolic Dysfunction in Patients with Q-Myocardial Infarction: Pathophysiological Mechanisms, Features of Remodeling, and Efficacy of Treatment with the Inclusion of ß-Adrenergic Blockers
  • Features of the clinical course, changes in systolic and diastolic function of the left ventricle and treatment of myocardial infarction with the Q wave in elderly patients
  • Influence of systemic inflammation on the course of atherosclerosis in connective tissue diseases
  • Pathophysiological mechanisms, diagnosis, treatment of acute and chronic heart failure of various genesis with reduced and preserved left ventricular ejection fraction
  • Drug prophylaxis of stroke and cardiovascular complications in patients with arterial hypertension
  • Condition of the musculoskeletal system and arterial stiffness in patients with rheumatological pathology and diseases of the cardiovascular system

 

ARTICLES OF THE STAFF OF THE DEPARTMENT OF INTERNAL MEDICINE No. 2, PUBLISHED IN JOURNALS INDEXED IN SCOPUS, WEB OF SCIENCE (2018-2024)

 

  • Dzhus M, Ivashkivsky O, Mikukst V, Parkishen S, Diadyk O. IgG4-Related Disease Misdiagnosed as Neoplasm. J Clin Rheumatol. 2019 Dec 24. doi: 10.1097/RHU.0000000000001244. [Epub ahead of print]; https://journals.lww.com/jclinrheum/Citation/9000/IgG4_Related_Disease_Misdiagnosed_as_Neoplasm.98832.aspx
  • Dzhus, M., Dzhus, M., Masnyi, M., Kulyk, M., Mostbauer, H., Ivashkivsky, O., Boyko, Y., Cherchenko, K., Geerinck, A., Reginster, J. Y., Bruyere,O., & Beaudart, C. Cross-sectional Evaluation of the Sarcopenia Quality of Life (SarQoL) Questionnaire: Translation and Validation of its Psychometric Properties. Annals of Geriatric Medicine and Research 2020; 24(2):139-147. Published online: June 15, 2020 DOI: https://doi.org/10.4235/agmr.20.0020

https://www.e-agmr.org/journal/view.php?doi=10.4235/agmr.20.0020

  • Kulyk, M.Dzhus. The association between presarcopenia and bone mineral density in adult patients with juvenile idiopathic arthritis. Annals of the Rheumatic Diseases 2021;80:1401-1402. DOI: 10.1136/annrheumdis-2021-eular.3641 May 19, 2021

http://dx.doi.org/10.1136/annrheumdis-2021-eular.3641

  • Dzhus, M. Kyluk, O. Ivashkivsky, T. Karasevska Annals of the Rheumatic Diseases 2020;79:844-845. Clinical and laboratory data and algorithm of management of adult patients with oligo- articular variants of JIA. DOI: 10.1136/annrheumdis-2020-eular.1870
  • Povoroznyuk V.V., Nishkumay O.I, Lazarieva K.P., Lazariev P.A. «Features of bone metabolism and their influence on arterial wall stiffness in postmenopausal women with controlled uncomplicated hypertension. / Geogian Medical News, N1(310). 2021. – P.87-93. Scopus, WebofScienceQ4 https://pubmed.ncbi.nlm.nih.gov/33658415/
  • Mostbauer, Halyna; Nishkumay, Olga; Rokyta, Oksana Rokyta O.; Vavryniuk, Valeriia. (2022). Warfarin resistance: possibilities to solve this problem. A case reportJournal of International Medical Research 50(6). 03000605221103959.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235305/

  • Marta B. Dzhus,· Tetiana A. Karasevska, Vira M. Tsaralunga, Alla V. Yurchenko, Olexiy I. Ivashkivsky. Behçet’s disease with intestinal involvement: case-based review. Rheumatology Internationalvolume 42, pages1653–1660 (2022) https://doi.org/10.1007/s00296-022-05152-x

https://link.springer.com/article/10.1007/s00296-022-05152-x

  • Dzhus, Marta, Mostbauer, Halyna/ Cardiovascular lesions in giant cell arteritis Reumatologiaю.60(6)399 – 407 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847101/

https://www.scimagojr.com/journalsearch.php?q=19752&tip=sid&clean=0

  • Kucherenko, Mykola; Mostbauer, Halyna; Strus, Oksana; Glushchenko, Victoria; Kovalchuk, Lina; Bobro, Elena; Shelest, Tatyana. International Maritime Health/ 73(3) 105–111 2022/ Multi-purpose transport monitoring of passenger-cargo traffic in Ukraine

https://www.scopus.com/record/display.uri?eid=2-s2.0-85139530512&origin=resultslist&sort=plf-f&src=s&sid=26f0c1b5ac29ea0c882f33da76c0ee72&sot=a&sdt=a&s=Multi-purpose+transport+monitoring+of+passenger-cargo+traffic+in+Ukraine&sl=72&sessionSearchId=26f0c1b5ac29ea0c882f33da76c0ee72

  • Kulyk, Myroslava; Novytska, Anna; Potemka, Ruslana; Ivashkivskyi, Oleksiy; Karasevska, Tetyana; Mostbauer, Halyna; Dzhus, Marta A Case Report of COVID-19-Related Dactylitis Combined with Chilblain-Like Acral Lesions Aktuelle Rheumatologie (efirst). doi:10.1055/a-2044-0440

https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-2044-0440.pdf

https://www.scimagojr.com/journalsearch.php?q=19132&tip=sid&clean=0

https://www.cambridge.org/core/journals/disaster-medicine-and-public-health-preparedness/article/impact-of-ukrainian-russian-war-on-health-care-and-humanitarian-crisis/4F3D9B7220368DD24A1D0F9B698DCD00

  • Nishkumay O.1,2, Mike K. S. Chan2, Nalapko Y.2, Grygorieva N.3, Nikitin O.1, Kordubailo I.1, Rudenko Iu. Stem-cell-based bioregenerative therapy of osteoporosis: literature review/ Cell and Organ Transplantology. 2023; 11(1):in press

https://doi.org/10.22494/cot.v11i1.146

  • Nishkumay, O. I., Rokyta, O. I., Kordubailo, I. A., Kovalenko, A. A., Govorov, A. O., Gorda, I. I., Dubynska, S. M., Vibla, M. Y., & Pidmurniak, N. O. (2022). Risk Stratification in Patients with Coronary Artery Disease: Timeliness of Invasive Interventions. Ukrainian Journal of Cardiovascular Surgery, 30(4), 26-32. https://doi.org/10.30702/ujcvs/22.30(04)/NR046-2632
  • Nishkumay O.I.; Mostbauer H.V.; Alekseenko O.O.; Moskalenko K.I.; Lazarev P.O.; Shevchuk M.I. Arterial stiffness, vascular calcification and osteoporosis – common mechanisms of interaction (literature review) Pain, Joints, Spine 12(2), 81–91 2022

https://www.scopus.com/record/display.uri?eid=2-s2.0-85163827813&origin=resultslist&sort=plf-f

  • Dzhus, Marta B.; Kulyk, Myroslava S.; Karasevska, Tetiana A. Mostbauer, Halyna.; Ivashkivskyi, Oleksiy I.; Potomka, Ruslana A.; Novytska, Hanna L. Sarcopenia and rheumatic diseases: is there any connection? Pain, Joints, Spine 12(4) 201-210/ – 2022

https://www.scopus.com/record/display.uri?eid=2-s2.0-85164101416&origin=resultslist&sort=plf-f

  • Nishkumay O.I.; Chan, Mike K.S.; Nalapko Yu.I.; Mostbauer H.V.; Alekseenko O.O.; Nikitin O.D.; Kordubailo I.A. (2023). Osteoporosis, arterial calcification, and kidney stone disease: modern anti-aging modalities (literature review) Pain, Joints, Spine 13 (2) 116 – 125.

https://www.scopus.com/record/display.uri?origin=recordpage&zone=relatedDocuments&eid=2-s2.0-85169310094&noHighlight=false&relpos=0

  • Kulyk, M., & Dzhus, M. (2023). Handgrip strength, physical activity, and body composition in young adults with juvenile idiopathic arthritis. PAIN, JOINTS, SPINE, 13(2), 101–107. https://doi.org/10.22141/pjs.13.2.2023.372

https://pjs.zaslavsky.com.ua/index.php/journal/article/view/372

  • Dzhus, M., Mostbauer, H. (2023). Coronary artery lesions in Takayasu arteritis Reumatologia; 61, 6: 460–472 doi: 10.5114/reum/176483

https://pubmed.ncbi.nlm.nih.gov/38322104/

  • Beaudart, C., Tilquin, N.,∙Abramowicz, P.,∙Baptista, F.,∙ Peng, D.J.,∙de Souza Orlandi, F.,∙Drey, M.,∙Dzhus, M.∙(2024) Quality of life in sarcopenia measured with the SarQoL questionnaire: A meta-analysis of individual patient data. Maturitas, Volume 180, 107902. https://doi.org/10.1016/j.maturitas.2023.107902

https://www.maturitas.org/article/S0378-5122(23)00508-X/fulltext

  • Mostbauer, H., Karasevska, T., Antonenko, L., Rudenko, I., & Bezrodnyi, A. (2023). Effects of oral anticoagulants on bone health (systematic literature review). PAIN, JOINTS, SPINE, 13(3), 201–209. https://doi.org/10.22141/pjs.13.3.2023.386

https://pjs.zaslavsky.com.ua/index.php/journal/article/view/386/429

  • Rudenko, I., Bezrodnyi, A.,  Mostbauer, H. (2024) Myocardial bridge of the left anterior descending coronary artery as a cause of acute coronary syndrome and ventricular tachycardia in a young patient. Case report. Ukrainian Therapeutical Journal 2. 44-53

http://utj.com.ua/article/view/306252

PUBLISHING ACTIVITY OF THE DEPARTMENT OF INTERNAL MEDICINE No2

 

  • Internal Medicine: Textbook: In 3 vols. Vol. 1 / K.M.Amosova, O.Ya.Babak, V.M.Zaitseva and others; Ed. Prof. K.M. Amosova. Kyiv, Meditsina Publ., 2008. – 1056 p.
  • Internal medicine: Textbook: In 3 vols. Vol. 2 / A.S. Svintsitsky, L.F. Konoplyova, Y.I. Feshchenko and others; Ed. Prof. K.M. Amosova. Kyiv, Meditsina Publ., 2009. – 1088 p.
  • Internal Medicine: Textbook: In 3 vols. – Vol.1. / E.N.Amosova, O.Ya.Babak, V.N.Zaitseva et al.; Ed. – K.: Medicine, 2008. – 1064 p.
  • Internal Medicine: Textbook: In 3 vols. – Vol. 2. / E.N.Amosova, O.Ya.Babak, V.N.Zaitseva et al.; Ed. – K.: Medicine, 2010. – 1128 p.
  • Practicum on Internal Medicine. Pic. / K.M. Amosova, L.F. Konopliova, L.L. Sidorova, G.V. Mostbauer and others. – Kyiv: Ukrainian Medical Bulletin, 2010 – 416 p.
  •  Pr aktikum z internalnoho mediciny: nauch. Pic. / K.M. Amosova, L.F. Konopliova, L.L. Sidorova, G.V. Mostbauer and others. – Kyiv: Ukrainian Medical Bulletin, 2012 – 416 p.
  • V.E. Kondratyuk, M.B. Dzhus Internal Medicine: Rheumatology: Textbook Kyiv: VSV “Medicine”, 2017. — 272 c.
  • Juvenile idiopathic arthritis. Ed.: Ya Boyko. Lviv: Svit, 2017. – 176 p. Authors: Boyko Y.E., Chernyshov V.P., Omelchenko L.I., Dzhus M.B. and others. (7 people in total).
  • Konopleva L.F., Reshotko D.A. Chronic pulmonary heart (cardiologist’s view). Kyiv, Kniga-Plus Publ., 2017. – 160 p.
  • Juvenile idiopathic arthritis. Ed.: Ya Boyko. – 2nd ed., Lviv: Svit; 2019. – 224 p. Authors: Boyko Y.E., Chernyshov V.P., Omelchenko L.I., Dzhus M.B. and others. (7 people in total).
  • Internal medicine : Part 1 : textbook for English-speaking students of higher medical schools / edited by Professor M. A. Stanislavchuk and Professor V. K. Sierkova. – Vinnytsya : Nova Knyha, 2019. – 408 p.
  • Secondary osteoporosis: monograph / Edited by: V. V. Povoroznyuk, N. V. Grigoryeva, N. V. Dedukh. Authors: Bystrytska M.A., Vayda V.M., Dzhus M.B., Dubetska G.S., Karasevska T.A., Klimovytskyi F.V., Mazur I.P., Martyniuk L.P., Martyniuk L.P., Masyk N.P., Nyshkumay O.I., Pankiv V.I., Povorozniuk V.V. – Kropyvnytskyi: Polium, 2021. – 524 p.
  • Unified (for Departments of Internal Medicine No. 1-4) methodological developments for practical classes in the discipline “Internal Medicine (including Clinical Pharmacology, Medical Genetics, Clinical Immunology and Allergology, Occupational Diseases)” in Ukrainian for 5th year students of medical faculties. A team of authors (from the Department of Internal Medicine No. 2: Associate Professor, Candidate of Medical Sciences Bezrodnyi A.B., Assistant, Candidate of Medical Sciences Bereza N.V., Assistant, Candidate of Medical Sciences Vasylenko O.V., Professor, Doctor of Medical Sciences Dzhus M.B., Associate Professor, Candidate of Medical Sciences Karasevska T.A., Assistant Professor Moskalenko Y.M., Associate Professor, Candidate of Medical Sciences Mostbauer G.V., Professor, Doctor of Medical Sciences Nishkumay O.I., Assistant, Candidate of Medical Sciences Rokita O.I., Assistant Chernyaeva K.I., Assistant, Candidate of Medical Sciences Shishkina N.V. Electronic edition. Kyiv, 2022. – 449 p.
  • Rheumatic diseases. Classification, standards of diagnosis and treatment edited by V.M. Kovalenko, Kyiv, Morion, 2021. – 399 p. Methodical recommendations for practical classes for 6th year higher education applicants.  Subject: Internal medicine, including phthisiology, endocrinology, emergency conditions in neurology, industrial medical practice (professional training), internal diseases. Content module 1. Management of patients with the main symptoms and syndromes in the cardiology clinic. Mostbauer, G. V., Dzhus, M. B., Rudenko, Y. V., Bezrodnyi, A. B., Zaitseva, O. E., Karasevska, T. A., Rokita, O. I., and Moskalenko, Yu. – 142 p. IRBNMU – Repository of Bogomolets National Medical University: Educational Publications of the Department of Internal Medicine No. 2 (librarynmu.com)

 

 

 

 

 

 

 

 

 

 

 

 

 

RESEARCH WORKS OF THE DEPARTMENT OF INTERNAL MEDICINE No2

 

  • Biochemical mechanisms of regulation of endothelial function in patients with different variants of heart failure (2005-2008).
  • Optimization of treatment and rehabilitation of patients with acute myocardial infarction through the development and implementation of comprehensive prevention of its early and late complications (2009-2011).
  • Pathophysiological mechanisms and new approaches to the treatment of various clinical forms of chronic heart failure (2011-2015).
  • “New technologies of medical and surgical prevention of stroke and cardiovascular complications in patients with arterial hypertension and atherosclerotic lesions of various vascular basins (2014 – 2016)
  • New methods of diagnosis and prevention of cardiovascular complications in patients with various clinical forms of heart failure (2016 – 2019).
  • New pathogenetic approaches to the diagnosis of heart failure with preserved left ventricular ejection fraction (2016 – 2019).
  • Study of the state of the musculoskeletal system, indicators of central arterial pressure and pulse wave propagation velocity in patients with rheumatological pathology and diseases of the cardiovascular system (2016 – 2019).
  • Structural and functional features of blood vessels and myocardium, skeletal system in patients with rheumatological pathology and diseases of the cardiovascular system (2020-2022).
  • Structural and functional changes in the cardiovascular, urinary and skeletal systems in patients with rheumatological and cardiac diseases under the influence of infectious and non-infectious factors (0123U101004; 2023-2025). The head of the research is Professor of the Department of Internal Medicine No. 2, Professor, Doctor of Medicine. n. Martha Juice; Responsible executor Head of the research Professor, Professor of the Department of Internal Medicine No. 2, Professor, Doctor of Medicine. n. Olga Nishkumay.