Department of Internal Medicine №3

MEDICAL AND ADVISORY WORK

Responsible person: Smirnova Olena Valeriivna, PhD, Associate Professor at the Department , of Internal Medicine 3

New directions in diagnostics:

– evaluation of anti-inflammatory and anti-destructive action of basic therapeutic remedies (BTR) in psoriatic arthritis by studying of the level of new connective tissue destruction markers dynamics;

– enhancement of the diagnostic algorithm in systemic necrotizing vasculitis;

– enhancement of diagnosis and treatment of spondyloarthritis based on the study of bone metabolism markers;

– determining the role of inflammation markers in the course of systemic lupus erythematosus monitoring;

– joints ultrasound in diagnosis and assessment of osteoarthritis and inflammatory arthropathy treatment efficacy;

– differential diagnosis of obstructive pulmonary disease using modern methods of assessment of the function of external respiration with the use of bronchodilator test on the SpiroCom apparatus of the National Aerospace University “KhAI”;

– modern methods of serological diagnostics (CRP, TNF-α, IL-4, IL-8 in sputum and blood serum) in the evaluation of patients with chronic obstructive pulmonary disease (COPD) treatment effectiveness;

– Holter ECG monitoring in patients with coronary artery and bronchopulmonary diseases;

– ultrasonographic investigation in the diagnostics of atherosclerotic and inflammatory lesions of the heart and blood vessels;

– investigation of amino acid and fatty acid membrane ATP-ases, hemorheological and immune status indicators to predict the course of COPD and myocardial infarction;

– creation of new and improvement of existing methods of diagnostics in nephrological patients;

– investigation of mechanisms of formation and progression of immune-mediated and bacterial-induced lesions of the kidneys, diabetic kidney disease;

– complex videoesophagogastroscopy, endoscopic ultrasonography of the stomach;

– biopsy diagnostics of esophagus, stomach and intestines diseases.

New directions of treatment

– differentiated selection of non-biological basic remedies  (NBBR) in various clinical and laboratory characteristics and duration of rheumatoid arthritis;

– elaboration of the of combined basic therapy methods of psoriatic arthritis;

– implementation and improvement of immunobiological therapy in inflammatory arthropathies;

– substantiation and elaboration of differentiated approaches to the prevention/ treatment of early atherogenesis in systemic inflammatory connective tissue lesions;

– improvement and standardization of local injection therapy methods and post-injection management of patients with inflammatory and degenerative joint lesions;

– participation in the examination, standardization and implementation of new pharmacotherapeutic technologies of the State Expert Centre of the Ministry of Health of Ukraine and the state formulary system by pulmonological and rheumatological work directions;

– implementation and approbation of the newest methods of pulmonary obstructive diseases treatment;

– improving the quality of life and better the course of patients with severe COPD through development and implementation of new mucoactive nebulizer therapy schemes;

– differentiated approach to cytoprotective therapy in acute myocardial infarction patients;

–hemomicrocirculatory and immune disorders medication correction in COPD patients;

– creation of new and improvement of existing methods of treatment, prevention and rehabilitation of nephrological profile patients;

–increased survival of patients with chronic kidney disease stage V treated by hemodialysis and peritoneal dialysis;

–methodological aspects development of improving of the specialized medical care organization for adults with urinary system diseases;

– creation of new and improvement of existing treatment, prevention and rehabilitation methods of gastroenterological profile patients .

CLINICAL BASES OF THE CHAIR

CNPE “Kyiv City Clinical Hospital №3”:

• cardiology department with an intensive care unit
• therapeutic department

Central Hospital of the Ministry of Internal Affairs of Ukraine:

• cardiology department
• pulmonology department
• gastroenterology department
• radiology department

State Institution “Territorial Medical Association of the Ministry of Internal Affairs of Ukraine in the Kyiv region”:

• therapeutic department №2
• cardiology department
• gastroenterology department
• pulmonology department

CNPE “Kyiv City Clinical Hospital №4”:

• therapeutic department №2

Kyiv Clinical Hospital on the railway transport №3:

• therapeutic department

Medical center “Universal clinic “Oberig “:

SI “Institute of Nephrology National Academy of Medical Science of Ukraine”

LLC “Nephrocenter”